The results of a 2016 mouse study suggested that a herbal gel containing Urtica dioica had pain-relieving and anti-edema effects without irritating the skin. However, there is a need for more recent studies in humans. Over a period of 3 months, people who took the supplement reported fewer symptoms and less frequent use of their anti-inflammatory medications than those in the placebo group. In a randomized controlled trial (RCT) from 2009, researchers gave 81 people with OA either a supplement that contained fish oil, vitamin E, and stinging nettle or a placebo. This means that stinging nettle could help reduce pain and inflammation in conditions such as arthritis. Stinging nettle hairs contain several chemicals that have pain-relieving and anti-inflammatory properties. Researchers have investigated the following properties of stinging nettle: According to the Arthritis Foundation, some people claim that the nettle can reduce inflammation, help improve osteoarthritis (OA) pain, and ease gout. One of the most popular uses of stinging nettle is treating arthritis symptoms.
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